What Happens If I Take Too Many Clopidogrel?

Does clopidogrel affect the kidneys?

Conclusions.

In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding..

Is there an alternative to clopidogrel?

1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

What are the side effects of taking clopidogrel?

Common side effects of clopidogrel can include:headaches or dizziness.nausea.diarrhoea or constipation.indigestion (dyspepsia)stomach ache or abdominal pain.nosebleeds.increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.

What foods should you avoid if you are on blood thinners?

If you take medicine for your heart, doctors recommend staying away from some foods because of the risk of interaction….Blood thinners: Eat fewer foods with vitamin KAsparagus.Broccoli.Brussels sprouts.Cauliflower.Green onions.Kale.Parsley.Spinach.

Is Plavix safe for kidneys?

Conclusions: Clopidogrel 75mg once daily was well tolerated in patients with either moderate or severe renal failure, and provided good inhibition of ADP-induced platelet aggregation without excessive extension of bleeding time. Dose adjustment in such patients does not appear to be required.

Does clopidogrel affect the liver?

The severity of liver injury associated with clopidogrel ranges from transient, mild serum enzyme elevations to clinically apparent acute hepatitis that can be severe and lead to death. Most cases resolve with drug withdrawal within 1 to 3 months.

Can you overdose on clopidogrel?

Clopidogrel is a commonly prescribed drug. Reports of overdose of clopidogrel were very rarely reported in the literature.

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

How does Clopidogrel affect the brain?

The blocked blood flow results in a lack of oxygen to your brain. This can lead to brain damage if it’s not treated right away. People who’ve had a stroke in the past have a higher risk of having another one. Plavix has been shown to reduce this risk in people using the drug.

Can I drink coffee with clopidogrel?

Conclusions: Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

What medications should be avoided with kidney disease?

5 Drugs You May Need to Avoid or Adjust if You Have Kidney…Cholesterol medications. The dosing of certain cholesterol medications, known as “statins”, may need to be adjusted if you have chronic kidney disease.Pain medications. … Anti-microbial meds. … Diabetes medications. … Upset stomach/antacid medications.

Can you ever stop taking blood thinners?

“With this rule we can confidently tell half of the women we see that they are at low risk of having another blood clot. This means they can stop taking blood thinners once their initial clot is treated, sparing them the cost, inconvenience and risks of taking life-long medication.”

How long should you take clopidogrel?

The new recommendation is that after 12 months if there is no evidence of major bleeding or other problems with clopidogrel + aspirin, it is suggested you continue that therapy for an additional 18 months. I know, it seems long.

What does clopidogrel do to your body?

Clopidogrel slows the blood’s clotting action by making platelets less sticky. Platelets are blood cells that stick together to block cuts and breaks in blood vessels. But in people at risk of heart attack or stroke, platelets can stick together inside already narrowed blood vessels to form a clot.

Does clopidogrel lower blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

What medications can affect the kidneys?

Which Drugs are Harmful to Your Kidneys?Pain Medications. Your kidneys could be damaged if you take large amounts of over-the-counter medications, such as aspirin, naproxen and ibuprofen. … Alcohol. … Antibiotics. … Prescription Laxatives. … Contrast Dye (used in some diagnostic tests such as MRIs) … Illegal Drugs. … What should you do?

Should clopidogrel be taken in the morning or evening?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.