How Does Encephalitis Lethargica Affect The Brain?

How do you detect encephalitis?

Diagnostic tests that may be performed to confirm the diagnosis of encephalitis may include the following:Magnetic resonance imaging (MRI).

Computed tomography scan (also called a CT or CAT scan).

Blood tests.Urine and stool tests.Sputum culture.

Electroencephalogram (EEG).

Spinal tap (also called a lumbar puncture).More items….

Is encephalitis Lethargica a virus?

Encephalitis lethargica is a viral epidemic encephalitis that occurred in many regions of the world during the period 1915–1926.

What are the early symptoms of encephalitis Lethargica?

Some of the symptoms of encephalitis lethargica include:High fever.Sore throat.Headache.Lethargy.Double vision.Delayed responses, both physically and mentally.Sleep inversion.Catatonia or unresponsiveness.More items…•

What is Post encephalitis?

Post-encephalitic Parkinsonism is a disease believed to be caused by a viral illness that triggers degeneration of the nerve cells in the substantia nigra. Overall, this degeneration leads to clinical parkinsonism.

Is encephalitis Lethargica curable?

There is little evidence so far of a consistent effective treatment for the initial stages, though some patients given steroids have seen improvement. The disease becomes progressive, with evidence of brain damage similar to Parkinson’s disease. Treatment is then symptomatic.

Why did Spanish flu kill so many?

Much of the high death rate can be attributed to crowding in military camps and urban environments, as well as poor nutrition and sanitation, which suffered during wartime. It’s now thought that many of the deaths were due to the development of bacterial pneumonias in lungs weakened by influenza.

What is the most common cause of encephalitis?

The most common causes of viral encephalitis are herpes simplex virus types 1 and 2, varicella zoster virus and enteroviruses, which cause gastrointestinal illness. Encephalitis can also result from certain viruses carried by mosquitoes, ticks and other insects or animals such as: West Nile virus.

What does a brain infection feel like?

Symptoms associated with bacterial meningitis can include severe headache, neck stiffness, high fever, nausea, vomiting, pain or discomfort when looking at bright lights, sleepiness, and confusion.

What caused the brain damage in Awakenings?

This story would become the basis of Sacks’s 1973 book, Awakenings, which was later made into a movie. The cause of encephalitis lethargica was never found, but studies of its victims have revealed swelling of the midbrain and basal ganglia and evidence of an autoimmune reaction to the tissue there.

Why does L dopa stop working Awakenings?

In a discovery that might turn out to be a game changer in Parkinson’s research, University of Alabama at Birmingham researchers discovered that DNA methylation causes L-DOPA to stop being effective after a few years, instead giving rise to dyskinesia — involuntary jerky movements making life even harder for patients.

Is L dopa still used?

Five decades after its introduction, L-DOPA is still the most effective and widely used drug to alleviate the symptoms of PD (4). In recent years, deep brain stimulation (DBS) has become a standard evidence-based therapy for severe movement disorders such as PD (5), tremor (6) and dystonia (7).

What is the disease in Awakenings?

(The disease was the subject of the book and film, “Awakenings.”) Information from th… Encephalitis lethargica is a disease characterized by high fever, headache, double vision, delayed physical and mental response, and lethargy.